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Page 1
Proline synthesis through PYCR1 is required to support cancer cell proliferation and survival in oxygen-limiting conditions.
Cell Rep. 2022 Feb 1;38(5):110320. doi: 10.1016/j.celrep.2022.110320.
Cell Rep. 2022.
PMID: 35108535
Free PMC article.
The MK2/3 cascade regulates AMPAR trafficking and cognitive flexibility.
Eales KL, Palygin O, O'Loughlin T, Rasooli-Nejad S, Gaestel M, Müller J, Collins DR, Pankratov Y, Corrêa SA.
Eales KL, et al.
Nat Commun. 2014 Aug 19;5:4701. doi: 10.1038/ncomms5701.
Nat Commun. 2014.
PMID: 25134715
Free PMC article.
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Verteporfin selectively kills hypoxic glioma cells through iron-binding and increased production of reactive oxygen species.
Eales KL, Wilkinson EA, Cruickshank G, Tucker JHR, Tennant DA.
Eales KL, et al.
Sci Rep. 2018 Sep 25;8(1):14358. doi: 10.1038/s41598-018-32727-1.
Sci Rep. 2018.
PMID: 30254296
Free PMC article.
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Oncogenic IDH1 Mutations Promote Enhanced Proline Synthesis through PYCR1 to Support the Maintenance of Mitochondrial Redox Homeostasis.
Hollinshead KER, Munford H, Eales KL, Bardella C, Li C, Escribano-Gonzalez C, Thakker A, Nonnenmacher Y, Kluckova K, Jeeves M, Murren R, Cuozzo F, Ye D, Laurenti G, Zhu W, Hiller K, Hodson DJ, Hua W, Tomlinson IP, Ludwig C, Mao Y, Tennant DA.
Hollinshead KER, et al. Among authors: eales kl.
Cell Rep. 2018 Mar 20;22(12):3107-3114. doi: 10.1016/j.celrep.2018.02.084.
Cell Rep. 2018.
PMID: 29562167
Free PMC article.
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The Role of p38 MAPK and Its Substrates in Neuronal Plasticity and Neurodegenerative Disease.
Corrêa SA, Eales KL.
Corrêa SA, et al. Among authors: eales kl.
J Signal Transduct. 2012;2012:649079. doi: 10.1155/2012/649079. Epub 2012 Jun 25.
J Signal Transduct. 2012.
PMID: 22792454
Free PMC article.
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